Differential regulation of GPR54 transcription by specificity protein-1 and partial estrogen response element in mouse pituitary cells
نویسندگان
چکیده
منابع مشابه
Differential regulation of estrogen receptor α expression in breast cancer cells by metastasis-associated protein 1.
Metastasis-associated protein 1 (MTA1) is a component of the nucleosome remodeling and histone deacetylase (HDAC) complex, which plays an important role in progression of breast cancer. Although MTA1 is known as a repressor of the transactivation function of estrogen receptor α (ERα), its involvement in the epigenetic control of transcription of the ERα gene ESR1 has not been studied. Here, we ...
متن کاملDifferential Regulation of Estrogen Receptor a Expression in Breast Cancer Cells by Metastasis-Associated Protein 1
Metastasis-associated protein 1 (MTA1) is a component of the nucleosome remodeling andhistone deacetylase (HDAC) complex, which plays an important role in progression of breast cancer. Although MTA1 is known as a repressor of the transactivation function of estrogen receptora (ERa), its involvement in the epigenetic control of transcription of the ERa gene ESR1 has not been studied. Here, we sh...
متن کاملpS2 Gene expression in HepG2 cells: complex regulation through crosstalk between the estrogen receptor alpha, an estrogen-responsive element, and the activator protein 1 response element.
The pS2 promoter is complex with binding sites for a number of protein factors that may participate in modulating its activity. The pS2 gene was transcriptionally activated by estrogens in HepG2 cells transformed (HepER3) to express the estrogen receptor alpha (ERalpha). The phorbol ester phorbol 12-myristate 13-acetate (PMA) stimulated pS2 expression in both HepER3 and the parental, non-ER-exp...
متن کاملThyroid hormone can increase estrogen-mediated transcription from a consensus estrogen response element in neuroblastoma cells.
Thyroid hormones (T) and estrogens (E) are nuclear receptor ligands with at least two molecular mechanisms of action: (i) relatively slow genomic effects, such as the regulation of transcription by cognate T receptors (TR) and E receptors (ER); and (ii) relatively rapid nongenomic effects, such as kinase activation and calcium release initiated at the membrane by putative membrane receptors. Ge...
متن کاملRegulation of Activating Transcription Factor-1 and the cAMP Response Element-binding Protein by Ca/Calmodulin-dependent Protein Kinases
The ability of activating transcription factor-1 (ATF1) or the cAMP response element-binding protein (CREB) to enhance transcription can be stimulated by increases in intracellular Ca concentrations. To identify protein kinases which may mediate the ability of Ca to activate these transcription factors, we compared the ability of constitutively active forms of several Ca/calmodulin-dependent pr...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Biochemical and Biophysical Research Communications
سال: 2010
ISSN: 0006-291X
DOI: 10.1016/j.bbrc.2010.02.026